HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 3-(Bromomethyl)quinolin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 3-(Hydroxymethyl)-1,2-dihydroquinolin-2-one | HCID 2764578 | — |
| Product | 3-(Bromomethyl)quinolin-2(1H)-one | HCID 336706 | — |
Reaction Steps
To 5 g of 3-hydroxymethylcarbostyril was added 50 ml of 47%-hydrobromic acid and the mixture was stirred at 70°-80° C. for 3 hours. After cooled the reaction mixture, the crystals precipitated were collected by filtration and were recrystallized from methanol to obtain 6 g of 3-bromomethylcarbostyril in the form of colorless needle-like crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE034722 |
| Source dataset | uspto-grants-1994_09 |
| ORD ID | ord-2885b0763d2e4f3a9d5bbcf48eb18366 |
| Source note | uspto-grants-1994_09 |