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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2225334Generated: October 31, 2026

Isatin → Acetylisatin

https://huagongshe.com/reaction/2225334

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsatinHCID 7054—
ReactantAcetic AnhydrideHCID 7918—
ProductAcetylisatinHCID 11321—

Reaction Steps

To 60 g of isatin was added 140 ml of acetic anhydride and the mixture was refluxed for 4 hours. The reaction mixture was cooled, and the crystals precipitated were collected by filtration, and washed with ether to obtain 58 g of N-acetylisatin.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUSRE034722
Source datasetuspto-grants-1994_09
ORD IDord-e1b5f5e7ff9a4b5f8eae3e0344f51ff4
Source noteuspto-grants-1994_09