Ethyl Acrylate → HCID 19004070, compound

Participants

Reaction Steps

A mixture of 3.30 g of 2-chloro-11-(1-piperazinyl)dibenzo[b,f][1,4]thiazepine and 1.20 g of ethyl acrylate in 17 ml of ethanol was refluxed for 3 hrs. The reaction mixture was concentrated and the residue was chromatographed on silica gel using a mixture of n-hexane and ethyl acetate (1:1) as an eluent to give 4.04 g of yellow crystals, which were recrystallized from isopropyl ether to give colorless needles, mp 79°-80° C.

Provenance & Evidence