HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → Methyl 2-(3-chloromethylphenoxy)propionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Methyl 2-(3-hydroxymethylphenoxy)propionate | HCID 18759680 | — |
| Catalyst | Pyridine | HCID 1049 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Methyl 2-(3-chloromethylphenoxy)propionate | HCID 18981053 | 88.8% |
Reaction Steps
By the method of Example 1, Step H, 1.98 g (0.0095 mole) of methyl 2-(3-hydroxymethylphenoxy)propionate and 1.24 g (0.0105 mole) of thionyl chloride were reacted in the presence of five drops of pyridine in 40 mL of methylene chloride, yielding 1.93 g of methyl 2-(3-chloromethylphenoxy)propionate as a yellow liquid. The NMR and IR spectra were consistent with the proposed structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05344812 |
| Source dataset | uspto-grants-1994_09 |
| ORD ID | ord-7b39b22a97f6423b8e50f4923c438265 |
| Source note | uspto-grants-1994_09 |