2,5-Dichlorobenzenesulfonyl chloride → 3-(2,5-Dichlorobenzenesulfonamido)-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)propan-2-ol

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Reaction Steps

Following the procedure described in the preceeding examples but using 2-(2,4-dichlorophenyl)-3-amino-1-(1H-1,2,4-triazol-1-yl)propan-2-ol and 2,5-dichlorobenzenesulfonylchloride, the title compound was obtained in a similar yield: mp 173°-174° C.; 1H NMR (80 MHz, CDCl3)δ(TMS) 8.05 (s, 1H, CH=N), 7.78 (s, 1H, CH=N), 8.0-7.0 (m, 6H, arom), 4.89 (AB system, Δv=0.42, J=14.5 Hz, 2H, CH2 -Tr), 3.87 (AB system, Δv=0.30, J=14 Hz, 2H, CH2NH). Anal calcd. for C17H14C14N4O3S: C 41.15%; H 2.84%; N 11.29%. Found: C 40.86%; H 3.06%; N 11.28%.

Provenance & Evidence