3,5-Dichloro-2-hydroxybenzenesulphonyl chloride → 3-(3,5-Dichloro-2-hydroxybenzenesulfonamido)-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)propan-2-ol

Participants

Reaction Steps

Following the procedure described in the preceeding examples but using 2-(2,4-dichlorophenyl)-3-amino-1-(1H-1,2,4-triazol-1-yl)propan-2-ol and 3,5-dichloro-2-hydroxybenzenesulfonylchloride, the title compound was obtained in a similar yield: mp dec; 1H NMR (80 MHz, MeOH-d4)δ(TMS) 8.4-8.1 (m, arom), 7.7-7.4 (m, CH=N, arom), 7.3-7.0 (m, arom), 4.76 (AB system, Δv=0.35, J=14.5 Hz, 2H, CH2 -Tr), 3.81 (AB system, Δv=0.72, J=14 Hz, 2H, CH2NH). Anal calcd. for C17H14Cl4N4O4S: C 39.87%; H 2.76%; N 10.94%. Found: C 39.75%; H 2.96%; N 10.90%.

Provenance & Evidence