2-Naphthalenesulfonyl chloride → HCID 19004254, compound

Participants

Reaction Steps

Following the procedure described in the preceeding examples but using 3-amino-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)propan-2-ol and 2-naphtalenesulfonylchloride, the title compound was obtained in a similar yield: mp 179°-180° C.; 1H NMR (80 MHz, CDCl3)δ(TMS) 8.34 (s, 1H, arom), 8.0-7.0 (m, 11H, arom, CH=N), 5.39 (t, J=6.5 Hz, 1H, NH), 4.95 (AB system, Δv=0.55, J=14.5 Hz, 2H, CH2 -Tr), 3.63 (double AB system, Δv=0.30, Jd=6.5 Hz, J=13.5 Hz, 2H, NCH2). Anal. calcd. for C21H18Cl2N4O3S: C 52.84%; H 3.80%; N 11.74%. Found: C 52.82%; H 3.98%; N 11.42%.

Provenance & Evidence