HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 1-(4-Hydroxy-3-methoxycinnamoyl)-4-methylpiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-(4-Acetoxy-3-methoxycinnamoyl)-4-methylpiperidine | HCID 54136428 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-(4-Hydroxy-3-methoxycinnamoyl)-4-methylpiperidine | HCID 54126025 | 75.4% |
Reaction Steps
Using 5.2 g of 1-(4-acetoxy-3-methoxycinnamoyl)-4-methylpiperidine (Example 55), 70 ml of methanol, and 5 g of potassium carbonate, a reaction similar to that conducted in Example 54 was carried out. As a result, 3.4 g of 1-(4-hydroxy-3-methoxycinnamoyl)-4-methylpiperidine (a compound of the present invention) was obtained as a yellow oil, which had the following physiochemical properties:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05344845 |
| Source dataset | uspto-grants-1994_09 |
| ORD ID | ord-be5f690cb98649b890deab6826caa0b7 |
| Source note | uspto-grants-1994_09 |