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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2225507Generated: October 26, 2026

Potassium Carbonate → 1-(4-Hydroxy-3-methoxycinnamoyl)-4-methylpiperidine

https://huagongshe.com/reaction/2225507

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant1-(4-Acetoxy-3-methoxycinnamoyl)-4-methylpiperidineHCID 54136428—
SolventMethanolHCID 887—
Product1-(4-Hydroxy-3-methoxycinnamoyl)-4-methylpiperidineHCID 5412602575.4%

Reaction Steps

Using 5.2 g of 1-(4-acetoxy-3-methoxycinnamoyl)-4-methylpiperidine (Example 55), 70 ml of methanol, and 5 g of potassium carbonate, a reaction similar to that conducted in Example 54 was carried out. As a result, 3.4 g of 1-(4-hydroxy-3-methoxycinnamoyl)-4-methylpiperidine (a compound of the present invention) was obtained as a yellow oil, which had the following physiochemical properties:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05344845
Source datasetuspto-grants-1994_09
ORD IDord-be5f690cb98649b890deab6826caa0b7
Source noteuspto-grants-1994_09