HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → N-(4-methylcyclohexyl)-4-hydroxy-3-methoxycinnamamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | N-(4-methylcyclohexyl)-4-acetoxy-methoxycinnamamide | HCID 67842174 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-(4-methylcyclohexyl)-4-hydroxy-3-methoxycinnamamide | HCID 54425771 | 83.4% |
Reaction Steps
Using 4.31 g of N-(4-methylcyclohexyl)-4-acetoxy-methoxycinnamamide (Example 61), 100 ml of methanol, and 10 g of potassium carbonate, a reaction similar to that conducted in Example 54 was carried out. As a result, 3.14 g of N-(4-methylcyclohexyl)-4-hydroxy-3-methoxycinnamamide (a compound of the present invention) was obtained as pale yellowish white crystal, which had the following physiochemical properties:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05344845 |
| Source dataset | uspto-grants-1994_09 |
| ORD ID | ord-6b4bff50e0984e71889e28b8820e221d |
| Source note | uspto-grants-1994_09 |