HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 178483832, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Diethyl chlorophosphate | HCID 13139 | — |
| Reactant | 2-Propenoic acid, 3-(3-nitrophenyl)- | HCID 68390 | — |
| Reactant | HCID 178483797 | HCID 178483797 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178483832 | HCID 178483832 | — |
Reaction Steps
Using 2.0 g of 3-nitrocinnamic acid, 1.9 ml of diethyl chlorophosphate, 3.5 ml of triethylamine, 60 ml of methylene chloride, 2.3 ml of N-(2-dimethylaminoethyl)-trans-4-methylcyclohexylamine (Example 78), and 0.04 g of 4-dimethylaminopyridine, a reaction similar to that conducted in Example 81 was conducted. As a result, 1.54 g of N-(2-dimethylaminoethyl)-N-(trans-4-methylcyclohexyl)-3-nitrocinnamamide (a compound of the present invention) was obtained as white crystal, which had the following physiochemical properties:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05344845 |
| Source dataset | uspto-grants-1994_09 |
| ORD ID | ord-ffef177d53994dc8bff0eadce686370a |
| Source note | uspto-grants-1994_09 |