HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178490545, compound → HCID 178490546, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178490545 | HCID 178490545 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178490546 | HCID 178490546 | 89.6% |
Reaction Steps
Using 1 g of N-(trans-4-methylcyclohexyl)-4-(2-morpholinoethoxy)-3-methoxycinnamamide (Example 144), 0.05 g of 10% palladium-carbon, and 100 ml of methanol, a reaction similar to that conducted in Example 147 was carried out. The product obtained was recrystallized from methylene chloride/ether, yielding 0.90 g of N-(trans-4methylcyclohexyl)-3-[4-(2-morpholinoethoxy)-3-methoxyphenyl]propionamide (a compound of the present invention) as white crystal, which had the following physiochemical properties:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05344845 |
| Source dataset | uspto-grants-1994_09 |
| ORD ID | ord-36893815392d4f588041168744b5991f |
| Source note | uspto-grants-1994_09 |