Potassium Carbonate → HCID 178471447, compound

Participants

Reaction Steps

Using 2 g of N-(trans-4-methylcyclohexyl)-4-hydroxy-3-methoxycinnamamide (Example 131), 1.4 g of potassium carbonate, 4 ml of ethyl 6-bromohexanoate, and 50 ml of methylisobutylketone, a reaction similar to that conducted in Example 171 was carried out. As a result, 2.89 g of N-(trans-4-methylcyclohexyl)-4-[5-(ethyoxycarbonyl)pentyloxy]-3-methoxycinnamamide (a compound of the present invention) was obtained as white crystal, which had the following physiochemical properties:

Provenance & Evidence