HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2225631Generated: October 31, 2026
(3-Bromopropyl)benzene → HCID 54243338, compound
https://huagongshe.com/reaction/2225631
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | (3-Bromopropyl)benzene | HCID 12503 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Benzeneacetic acid, 4-hydroxy-alpha-oxo-, methyl ester | HCID 3084696 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 54243338 | HCID 54243338 | — |
Reaction Steps
A stirred mixture of 4-hydroxy-alpha-oxobenzeneacetic acid methyl ester (0.724 g) in dimethylformamide (10 mL) under argon was treated with 55% sodium hydride (0.175 g), stirred for 15 minutes and treated with 3-bromo-1-phenylpropane. The mixture was heated at 60° C. overnight and worked up as in Example 20. The material was purified by HPLC (dichloromethane-hexane; 4:1) to provide 0.65 g of 4-[(3-phenylpropyl)oxy]-alpha-oxobenzeneacetic acid methyl ester as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05344843 |
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| Source dataset | uspto-grants-1994_09 |
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| ORD ID | ord-6ccb4170d3c54b60af35ac88b26d9675 |
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| Source note | uspto-grants-1994_09 |
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