HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 54432009, compound → HCID 19004495, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 54432009 | HCID 54432009 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | HCID 19004495 | HCID 19004495 | 85.3% |
Reaction Steps
A mixture of 4- [[2-(4-fluorophenoxy)ethyl]oxy]-alpha-oxobenzeneacetic acid methyl ester (0.65 g) in methanol and 0.5N sodium hydroxide (8 mL) was treated as in Example 19. Extraction with dichloromethane-diethyl ether provided solids which were crystallized from dichloromethane-hexane to give 0.53 g of colorless 4-[[2-(4-fluorophenoxy) ethyl]oxy]-alpha-oxobenzeneacetic acid, mp 97°-98° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05344843 |
| Source dataset | uspto-grants-1994_09 |
| ORD ID | ord-5151374e78414ebc8ab1834e5a85fe8f |
| Source note | uspto-grants-1994_09 |