HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[[2-(4-Chlorophenoxy)ethyl]oxy]-alpha-oxobenzeneacetic acid methyl ester → 4-[[2-(4-Chlorophenoxy)ethyl]oxy]-alpha-oxobenzeneacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[[2-(4-Chlorophenoxy)ethyl]oxy]-alpha-oxobenzeneacetic acid methyl ester | HCID 54448731 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 4-[[2-(4-Chlorophenoxy)ethyl]oxy]-alpha-oxobenzeneacetic acid | HCID 19004325 | 91.3% |
Reaction Steps
A mixture of 4-[[2-(4-chlorophenoxy)ethyl]oxy]-alpha-oxobenzeneacetic acid methyl ester (0.72 g) in methanol and 0.5N sodium hydroxide (8 mL) was treated as in Example 19. Extraction provided solids which were crystallized from diethyl ether-hexane to give 0.63 g of colorless 4-[[2-(4-chlorophenoxy)ethyl]oxy]-alpha-oxobenzeneacetic acid, mp 121°-122° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05344843 |
| Source dataset | uspto-grants-1994_09 |
| ORD ID | ord-29e5db7793474044a8da7f80a54c1a78 |
| Source note | uspto-grants-1994_09 |