HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[[2-[4-(1,1'-Biphenyl)oxy]ethyl]oxy]-alpha-oxobenzeneacetic acid methyl ester → alpha-Oxo-4-[[2-(4-phenoxyphenoxy)ethyl]oxy]benzeneacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[[2-[4-(1,1'-Biphenyl)oxy]ethyl]oxy]-alpha-oxobenzeneacetic acid methyl ester | HCID 53881335 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | alpha-Oxo-4-[[2-(4-phenoxyphenoxy)ethyl]oxy]benzeneacetic acid | HCID 19004268 | 136.8% |
Reaction Steps
A mixture of 4-[[2-[4-(1,1'-biphenyl)oxy]ethyl]oxy]-alpha-oxobenzeneacetic acid methyl ester (0.8 g) in methanol (20 mL) and 0.5N sodium hydroxide (8 mL) was treated as in Example 19. Extraction provided solids which were crystallized from diethyl etherhexane to give 0.55 g of colorless alpha-oxo-4-[[2-(4-phenoxyphenoxy)ethyl]oxy]benzeneacetic acid, mp 124°-126° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05344843 |
| Source dataset | uspto-grants-1994_09 |
| ORD ID | ord-e8f96ee4fb324cb29366838199d8a999 |
| Source note | uspto-grants-1994_09 |