HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[[3-(2-Naphthalenyl)propyl]oxy]-alpha-oxobenzeneacetic acid methyl ester → 4-[[3-(2-Naphthalenyl)propyl]oxy]-alpha-oxobenzeneacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[[3-(2-Naphthalenyl)propyl]oxy]-alpha-oxobenzeneacetic acid methyl ester | HCID 54003296 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 4-[[3-(2-Naphthalenyl)propyl]oxy]-alpha-oxobenzeneacetic acid | HCID 19004419 | 86.8% |
Reaction Steps
A mixture of 4-[[3-(2-naphthalenyl)propyl]oxy]-alpha-oxobenzeneacetic acid methyl ester (0.6 g) in methanol (10 mL) and 0.5N sodium hydroxide (4 mL) was treated as in Example 19. Extraction with dichloromethane provided material which was crystallized from dichloromethane-hexane to give 0.5 g of colorless 4-[[3-(2-naphthalenyl)propyl]oxy]-alpha-oxobenzeneacetic acid, mp 123°-124° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05344843 |
| Source dataset | uspto-grants-1994_09 |
| ORD ID | ord-1a0c2605c9254d61910b78dc97deaf35 |
| Source note | uspto-grants-1994_09 |