Hydrochloric Acid → HCID 19004513, compound

Participants

Reaction Steps

To a solution of 4-[[2-[2-[(2,2-dimethyl-1-oxobuyloxy)methyl]-6-methylphenoxy]ethyl]oxy]-alpha-oxobenzeneacetic acid [2:1]hydrate (0.032 g) in methanol (10 mL) was added aqueous 1N sodium hydroxide (1.0 mL). After 18 hours at 40° C., the reaction was acidified with 1N hydrochloric acid (2 mL), then concentrated in vacuo to ~2 mL and extracted with dichloromethane. The organic extract was evaporated to provide 0.014 g of 4-[[2-[2-(hydroxymethyl)-6-methylphenoxy]ethyl]oxy]-alpha-oxobenzeneacetic acid as a white solid.

Provenance & Evidence