Acetone → Benzoylacetone

HRID 2225982Notes

Reaction equation

HRID 2225982 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)(=[O:3])[CH3:2].[CH3:10][C:11](C)=[O:12]>CS(C)=O.O1CCCC1>[C:4]1([C:1](=[O:3])[CH2:2][C:11](=[O:12])[CH3:10])[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 180AcetoneHCID 7410Acetophenone

Product 1

HCID 7166Benzoylacetone

Reagents, catalysts & solvents 1

HCID 21830753dimethylsulfoxide THFSolvent

Procedure

The procedure of Example 1 is repeated, using in place of acetophenone 17.4 g of acetone and increasing the amount of solvent from 100 g to 150 g of dimethyl sulfoxide/tetrahydrofuran.

Sources & evidence

ORD record
ord-b7b701b39b0a44d68eeaa397e3aaeed8
Source dataset
uspto-grants-1994_09
Patent number
US05344992

Reaction notes

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