Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | Methyl Benzoate | HCID 7150 | — |
| Reactant | Acetophenone | HCID 7410 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | Dibenzoylmethane | HCID 8433 | — |
Reaction Steps
An apparatus as described in Example 1 is charged with 18.0 g of sodium methylate (97%), 100 g of DMSO, 100 g of dioxane and 6 g of methanol and the mixture is cooled to 0° C. Then a mixture of 45 g of methyl benzoate and 36 g of acetophenone are added dropwise over 35 minutes. The reaction mixture is then stirred for ca. 45-60 minutes at 30° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05344992 |
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| Source dataset | uspto-grants-1994_09 |
|---|
| ORD ID | ord-5e59714a730c43e49f084563caf40d22 |
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| Source note | uspto-grants-1994_09 |
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