Sodium Hydroxide → HCID 86748145, compound

HRID 2226388Notes

Reaction equation

HRID 2226388 reaction equation
[C:1]([CH:6]([NH:16][C@H:17]([C:19]([N:21]1[CH:29]2[CH:24]([CH2:25][CH2:26][CH2:27][CH2:28]2)[CH2:23][C@H:22]1[C:30]([OH:32])=[O:31])=[O:20])[CH3:18])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([Cl:15])=[CH:11][CH:10]=1)([O:3]CC)=[O:2].[OH-].[Na+]>CO>[C:1]([CH:6]([NH:16][C@H:17]([C:19]([N:21]1[CH:29]2[CH:24]([CH2:25][CH2:26][CH2:27][CH2:28]2)[CH2:23][C@H:22]1[C:30]([OH:32])=[O:31])=[O:20])[CH3:18])[CH2:7][CH2:8][C:9]1[CH:10]=[CH:11][C:12]([Cl:15])=[CH:13][CH:14]=1)([OH:3])=[O:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 86748146HCID 86748146, compound

Product 1

HCID 86748145HCID 86748145, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Treat the ester (prepared as described in Example 3) with sodium hydroxide in methanol as described in Example 2 to yield the title compound.

Sources & evidence

ORD record
ord-7c8d3a3e573c43cab0a4caf0749ae0db
Source dataset
uspto-grants-1994_09
Patent number
US05348944

Reaction notes

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