Sodium Hydroxide → HCID 44316862, compound

HRID 2226399Notes

Reaction equation

[C:1]([CH:6]([NH:15][C@H:16]([C:18]([N:20]1[CH2:28][CH:27]2[CH:22]([CH2:23][CH2:24][CH2:25][CH2:26]2)[C@H:21]1[C:29]([OH:31])=[O:30])=[O:19])[CH3:17])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)([O:3]CC)=[O:2].[OH-].[Na+]>>[C:1]([CH:6]([NH:15][C@H:16]([C:18]([N:20]1[CH2:28][CH:27]2[CH:22]([CH2:23][CH2:24][CH2:25][CH2:26]2)[C@H:21]1[C:29]([OH:31])=[O:30])=[O:19])[CH3:17])[CH2:7][CH2:8][C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)([OH:3])=[O:2]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 67812981HCID 67812981, compound

Product 1

HCID 44316862HCID 44316862, compound

Procedure

As described in Example 2 treat N-(1-carboethoxy-3-phenylpropyl-(S)-alanyl]octahydroisoindole-1(S)-carboxylic acid (prepared as described in Example 18) with sodium hydroxide to obtain the title compound.

Sources & evidence

ORD record: ord-10d9a2cb6d17460eac72f72c396c823e
Source dataset: uspto-grants-1994_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05348944

Reaction notes

Loading…