HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 7-(N-benzyloxycarbonylglycyl)-1,4-dithia-7-azaspiro[4.4]nonane-8(S)-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 7-(N-benzyloxycarbonylglycyl)-1,4-dithia-7-azaspiro[4.4]nonane-8(S)-carboxylic acid, ethyl ester | HCID 13373629 | — |
| Product | 7-(N-benzyloxycarbonylglycyl)-1,4-dithia-7-azaspiro[4.4]nonane-8(S)-carboxylic acid | HCID 13373627 | — |
Reaction Steps
Hydrolyze 1.43 g of 7-(N-benzyloxycarbonylglycyl)-1,4-dithia-7-azaspiro [4.4]nonane-8(S) -carboxylic acid, ethyl ester (prepared as described in paragraph B next above) with sodium hydroxide as described in Example 23 to obtain 7-(N-benzyloxycarbonylglycyl)-1,4-dithia-7-azaspiro[4.4]nonane-8(S)-carboxylic acid, a colorless oil, [α]D26 -7.9°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05348944 |
| Source dataset | uspto-grants-1994_09 |
| ORD ID | ord-691718034b9b43f2945232df7af22836 |
| Source note | uspto-grants-1994_09 |