HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67788598, compound → 1-(Phenylmethyl) (2S)-5-oxo-1,2-piperidinedicarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67788598 | HCID 67788598 | — |
| Reactant | Jones' reagent | HCID 131709961 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 1-(Phenylmethyl) (2S)-5-oxo-1,2-piperidinedicarboxylate | HCID 18654787 | — |
Reaction Steps
Dissolve 1 -benzyloxycarbonyl-5-hydroxy-(S)-pipecolic acid (prepared from 5-hydroxy-(S)-pipecolic acid in 2N sodium hydroxide solution treated with benzylchlorformate in diethyl ether) in acetone and treat with Jones reagent to obtain 1-benzyloxycarbonyl-5-keto-(S)-pipecolic acid. Then esterify in methanol to give the respective methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05348944 |
| Source dataset | uspto-grants-1994_09 |
| ORD ID | ord-46399973e14c46f0bffeea9d39f41558 |
| Source note | uspto-grants-1994_09 |