Water → HCID 18965330, compound

Participants

Reaction Conditions

Reaction Steps

A suspension containing 158 mmol of lithium aluminum hydride in 150 ml of tetrahydrofuran is added at 20° C. to 15.8 mmol of the compound of Example 20 in 50 ml of tetrahydrofuran. The combined mixture is maintained for 9 hours at 20° C. and then hydrolyzed with 30 ml of water and 12 ml of 10% sodium hydroxide solution. After filtration and evaporation, the expected product is obtained in the form of an oil.

Provenance & Evidence