m-Chloroperbenzoic acid → HCID 18965263, compound

Participants

Reaction Steps

Dissolve 3-chloropropyl isopentyl sulfide (800 mg, 4.43 mmol) in methylene chloride (25 mL) and place under nitrogen atmosphere. Add a solution of metachloroperbenzoic acid (1.53 g, 8.85 mmol) in methylene chloride (25 mL). Stir at room temperature overnight. Add additional meta-chloroperbenzoic acid (1.0 g) in methylene chloride (25 mL). Stir at room temperature overnight. Treat with aqueous sodium metabisulfite (until negative starch-iodide test) and separate the layers. Wash the organic phase with saturated sodium hydrogen carbonate until basic and dry (MgSO4). Evaporate the solvent in vacuo to yield 710 mg (75.4%) of 3-chloropropyl isopentyl sulfone as a yellow oil which crystallizes; MS (CI/CH4) m/z 213(M+1), 177(M+1-HCl).

Provenance & Evidence