HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 53962617, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | ethyl (2S)-2-acetyloxy-4-hydroxybutanoate | HCID 11171486 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 53962617 | HCID 53962617 | 89.3% |
Reaction Steps
(S)-2-Acetoxy-4-hydroxybutanoic acid ethyl ester (0.5 g, 2.6 mmol) in pyridine (1 ml) was added to a solution of (4-methylphenyl)sulphonyl chloride (0.53 g, 2.76 mmol) in pyridine (1 ml) at 5°. After 16 h at 5° ethyl acetate and water were added, the organic layer was separated, washed with hydrochloric acid (2N), dried (MgSO4) and the solvent evaporated to give the sub-title ester (0.8 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05348978 |
| Source dataset | uspto-grants-1994_09 |
| ORD ID | ord-cd869c0f7fed44b5825da87b3b133623 |
| Source note | uspto-grants-1994_09 |