反应详情

To a solution of cyclohexyl 2-bromoacetate (15.6 g, 0.07 mole) in dimethylsulfoxide (120 ml), sodium benzenesulfinate dihydrate (15 g, 0.075 mole) was added in a small portion at 30°-40° C., and stirring was continued at 60° C. for 6 hours. The resultant mixture was poured into ice-cold H2O (1.5 l). The precipitate was filtered, washed with H2O and dried to afford 15.3 g of cyclohexyl 2-phenylsulfonylacetate as white crystals.

1. filtrationThe precipitate was filtered
2. washwashed with H2O
3. customdried