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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2226901Generated: October 30, 2026

Ninhydrin → (RS)-4-Methoxy-3-(phenylmethoxy)phenylalanine

https://huagongshe.com/reaction/2226901

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNinhydrinHCID 10236—
Reactant(RS)-5-[[4-Methoxy-3-(phenylmethoxy)phenyl]methyl]-2,4-imidazolidinedioneHCID 15296732—
Solventchloroform methanol HOAcHCID 21866353—
Product(RS)-4-Methoxy-3-(phenylmethoxy)phenylalanineHCID 15296733—

Reaction Steps

This compound is prepared from the corresponding hydantoin derivative (Example 7) by a procedure similar to that in Example 9; tlc (1:5:20 acetic acid-methanol-chloroform system); Rf 0.4 (ninhydrin).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05350757
Source datasetuspto-grants-1994_09
ORD IDord-b9067ec5149644f6a2a47e5941d0dea1
Source noteuspto-grants-1994_09