Ethanol → HCID 14512773, compound

Participants

Reaction Steps

To a stirred solution of 1,2-dichloro-1,1,2,3,3,4,4,-heptafluoro-6-iodohexane (370.0 g) and ethanol (400 mL) was added dropwise a solution of potassium hydroxide (56.0 g), ethanol (300 mL) and water (20 mL) at 80°-90° C. over 40 minutes. After the addition was complete, the reaction mixture was refluxed for 1 hour and then poured into water. Lower layer was separated and washed with water to give desired product (233.5 g) . 19F NMR: -63.9 (m, 2F) , -111.9 (m, 2F) , -116.2 (m, 2F) , -130.5 (m, 1F); 1H NMR: 5.72 to 6.10 (m) . IR: 1651 (m) , 1422 (s) , 1180 (s) , 1055 (s) , 1019 (s) , 1002 (s) , 980 (s) .

Provenance & Evidence