HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formic Acid → 3-(4-Nitrophenyl)propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formic Acid | HCID 284 | — |
| Reactant | 4-Nitrobenzaldehyde | HCID 541 | — |
| Reactant | 2,2-Dimethyl-1,3-dioxane-4,6-dione | HCID 16249 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 3-(4-Nitrophenyl)propanoic acid | HCID 85526 | — |
Reaction Conditions
| Temperature | 105 °C |
|---|
Reaction Steps
3.60 g (0.025 mol) of Meldrum's acid and 3.8 g (0.025 mol) of p-nitrobenzaldehyde were weighed in to 25 ml of the mixture of formic acid and triethylamine prepared as described in Example 1. The reaction mixture was heated to 105° C. during 1 hour and reacted at the same temperature for 1 hour. The product was isolated according to Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05350872 |
| Source dataset | uspto-grants-1994_09 |
| ORD ID | ord-74e0d36ba6914cb69f918afb436c4996 |
| Source note | uspto-grants-1994_09 |