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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2227037Generated: November 1, 2026

Diethyl Ether → HCID 10008954, compound

https://huagongshe.com/reaction/2227037

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
Reactant5-MethylthiazoleHCID 137980—
ReactantN-[3-(Bromomethyl)phenyl]-4-(tetradecyloxy)-benzeneacetamideHCID 10052253—
SolventTolueneHCID 1140—
ProductHCID 10008954HCID 1000895488.6%

Reaction Steps

A mixture of 3.6 g of N-[3-(bromomethyl)-phenyl]-4-(tetradecyloxy)benzeneacetamide and 3.46 g of 5-methylthiazole in 25 ml of toluene is refluxed under inert gas for 1.5 hours, cooled and poured into 200 ml of ether. The organic layer is decanted and the solid washed with ether and collected to give 3.8 g of the desired product as a white solid, m.p. 173°-175° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05350759
Source datasetuspto-grants-1994_09
ORD IDord-e8804ca5d5234031a2775ed7f1550a5f
Source noteuspto-grants-1994_09