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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2227080Generated: November 1, 2026

Imidazo(1,2-a)pyridine → HCID 19925050, compound

https://huagongshe.com/reaction/2227080

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazo(1,2-a)pyridineHCID 78960—
ReactantN-[3-(Bromomethyl)phenyl]-4-(tetradecyloxy)-benzeneacetamideHCID 10052253—
SolventAcetonitrileHCID 6342—
ProductHCID 19925050HCID 1992505081.4%

Reaction Steps

A mixture of 1.5 g of N-[3-(bromomethyl)phenyl]-4-(tetradecyloxy)benzeneacetamide and 1.03 g of imidazo[1,2-a]pyridine in 25 ml of acetonitrile is refluxed under argon for 3.5 hours. The solvent is evaporated and the residue stirred with ether and collected by centrifugation. The solid is washed several times with ether and vacuum dried to give 1.5 g of the desired product as a white powder, m.p 133°-135° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05350759
Source datasetuspto-grants-1994_09
ORD IDord-b69d95fb58764dca8556431735fdd0b8
Source noteuspto-grants-1994_09