HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-{2-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-1,3-thiazol-5-yl}acetamide → n-{5-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1h-3-benzazepin-7-yl)oxy]-2-thienyl}acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-{2-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-1,3-thiazol-5-yl}acetamide | HCID 10338403 | — |
| Reactant | 3-Cyclobutyl-7-[(5-nitro-2-thienyl)oxy]-2,3,4,5-tetrahydro-1H-3-benzazepine | HCID 10382895 | — |
| Product | n-{5-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1h-3-benzazepin-7-yl)oxy]-2-thienyl}acetamide | HCID 10043835 | — |
Reaction Steps
Example 212 (E212) was prepared from 3-cyclobutyl-7-[(5-nitro-2-thienyl)oxy]-2,3,4,5-tetrahydro-1H-3-benzazepine (E211) using an analogous method to that described for Example 210 (E210); MS (ES+) m/e 357 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08207331B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-8c58790cea084f4098a486e0f86ec4b3 |
| Source note | uspto-grants-2012_06 |