4-Pentyl-3-cyclohexenylcarboxylic acid → 4-(5-Decyl-2-pyrimidyl)phenol 4-pentyl-3-cyclohexenylcarboxylate
Reaction equation
[CH2:1]([C:11]1[CH:12]=[N:13][C:14]([C:17]2[CH:22]=[CH:21][C:20]([OH:23])=[CH:19][CH:18]=2)=[N:15][CH:16]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[CH2:24]([C:29]1[CH2:34][CH2:33][CH:32]([C:35]([OH:37])=[O:36])[CH2:31][CH:30]=1)[CH2:25][CH2:26][CH2:27][CH3:28].C(C1CCC(C(OC2C=CC(CCC3CCC(CCC=C(C)C)=CC3)=CC=2)=O)CC=1)CCCC>>[CH2:1]([C:11]1[CH:12]=[N:13][C:14]([C:17]2[CH:18]=[CH:19][C:20]([OH:23])=[CH:21][CH:22]=2)=[N:15][CH:16]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[CH2:24]([C:29]1[CH2:34][CH2:33][CH:32]([C:35]([O-:37])=[O:36])[CH2:31][CH:30]=1)[CH2:25][CH2:26][CH2:27][CH3:28]Participants
4
Reactant 3
Product 1
Procedure
The reaction between 4-(5-decyl-2-pyrimidyl)phenol (prepared essentially according to the procedure of H. Zaschke and R. Stolle, Z. Chem. 15, 441-43 (1975)) and 4-pentyl-3-cyclohexenylcarboxylic acid is essentially that used for the synthesis of ester 2J.
Workup
- customprepared essentially
Sources & evidence
- ORD record
- ord-9afc8b4d2fb44d789f9316d103d29d52
- Source dataset
- uspto-grants-2002_07
- Patent number
- US06413448B1
Reaction notes
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