O-Phenylenediamine → HCID 135744193, compound

Participants

Reaction Steps

3.479 g (17.64 mmol) 4-(N,N-Diethylamino)-salicylaldehyde are added at 5° C. in portions to a solution of 1.927 g (17.64 mmol) 1,2-phenylenediamine in 18 ml ethanol, the temperature being kept below 10° C. The resultant dark red suspension is stirred for 8 hours at room temperature and concentrated to dryness in vacuo. The crude product (6.34 g) is resolved by column chromatography (n-hexane/ethyl acetate 65:35). Yield: 1.27 g (26%), golden yellow crystalls.

Provenance & Evidence