HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Piperidone → 1-[6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-3-pyridinyl]-2-piperidinone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Piperidone | HCID 12665 | — |
| Edukt | Gsk-239512 | HCID 9976892 | — |
| Edukt | 1H-3-Benzazepine, 3-cyclobutyl-2,3,4,5-tetrahydro-7-[(5-iodo-2-pyridinyl)oxy]- | HCID 57440294 | — |
| Produkt | 1-[6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-3-pyridinyl]-2-piperidinone | HCID 10045991 | — |
Reaktionsschritte
Example 218 (E218) was prepared from 3-cyclobutyl-7-[(5-iodo-2-pyridinyl)oxy]-2,3,4,5-tetrahydro-1H-3-benzazepine (E207) and 2-piperidinone using the method described for Example 217 (E217); MS (ES+) m/e 392 [M+H]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08207331B2 |
| Quelldatensatz | uspto-grants-2012_06 |
| ORD ID | ord-da12da94bfd14e20980a556c4c68ff45 |
| Quellennotiz | uspto-grants-2012_06 |