HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18403163, compound → HCID 9949326, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18403163 | HCID 18403163 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 9949326 | HCID 9949326 | 89% |
Reaction Steps
2,4-Di(benzyloxycarbonyl)butyl(3-phenylpropyl)phosphinic acid (15) (1.4 g, 2.8 mmol) in 20 mL of water containing 150 mg of 10% Pd/C was hydrogenated at 40 psi overnight. Filtration through a Celite pad followed by evaporation on high vacuum gave 0.8 g (89%) of 2-[(3-phenylpropylhydroxyphosphinyl)methyl]pentanedioic acid (4, R=CH2CH2CH2Ph) as a light yellow viscous oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06413948B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-cb8131c305aa440cab201c7be39e63be |
| Source note | uspto-grants-2002_07 |