Morpholine → HCID 15907531, compound

HRID 2227342Notes

Reaction equation

HRID 2227342 reaction equation
[CH2:1]([N:3]1[C:11]2[N:10]=[C:9]([CH2:12][CH3:13])[NH:8][C:7]=2[C:6](=S)[NH:5][C:4]1=[S:15])[CH3:2].[NH:16]1[CH2:21][CH2:20][O:19][CH2:18][CH2:17]1>CC(C)=O>[CH2:1]([N:3]1[C:11]2[N:10]=[C:9]([CH2:12][CH3:13])[NH:8][C:7]=2[C:6]([N:16]2[CH2:21][CH2:20][O:19][CH2:18][CH2:17]2)=[N:5][C:4]1=[S:15])[CH3:2]

Participants

4

Reactant 2

HCID 8083MorpholineHCID 15907530HCID 15907530, compound

Product 1

HCID 15907531HCID 15907531, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

The product of stage (i) (14.42 g) was refluxed in 78.4 ml (900 mmoles) of morpholine for 30 hours. After cooling to room temperature the reaction product was suspended in 100 ml of acetone and the title product (16.49 g) collected and washed.

Workup

  1. customthe title product (16.49 g) collected
  2. washwashed

Sources & evidence

ORD record
ord-01ebdd2061314dc5be80a0cb5a8218a2
Source dataset
uspto-grants-2002_07
Patent number
US06413975B1

Reaction notes

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