HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-(4-(hydroxymethyl)phenyl)propanoate → Methyl 3-(4-formylphenyl)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-(4-(hydroxymethyl)phenyl)propanoate | HCID 18473826 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Methyl 3-(4-formylphenyl)propanoate | HCID 11063253 | 91.1% |
Reaction Steps
A suspension of methyl 4-hydroxymethylhydrocinnamate (2.34 g) and manganese dioxide (21.0 g) in 40 ml dichloromethane was stirred at room temperature for 17 hours. Manganese dioxide was filtered off onto Celite. The filtrate was evaporated and dried under reduced pressure to give methyl 4-formylhydrocinnamate (2.11 g, 91%) as a colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06413995B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-a146bf07198c4680a4109f32c7944ebf |
| Source note | uspto-grants-2002_07 |