HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-5-methylamino-6-nitro-pyridine → HCID 18412465, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-5-methylamino-6-nitro-pyridine | HCID 14929578 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 18412465 | HCID 18412465 | — |
Reaction Steps
8.35 g (50 mmol) of 2-Methyl-5-methylamino-6-nitropyridine (Heterocycles 38, 529 (1994)) were dissolved in 300 l ethyl acetate and hydrogenated with 1.5 g Raney nickel for 3.5 hours at room temperature. Then the catalyst was filtered off and the filtrate was evaporated down. After crystallization of the resulting residue from petroleum ether, 5.75 g (84% of theory) were obtained as olive-green crystals. C7H11N3 (137.20). Melting point: 112-113° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06414008B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-6b89f5081e4f438187fbfbf24fc0da0c |
| Source note | uspto-grants-2002_07 |