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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2227635Generated: October 31, 2026

Hydrochloric Acid → 1-Methyl-2-[(4-amidinophenyl)oxymethyl]benzimidazol-5-yl-sulfonic acid-n-methyl-n-(1-methylpiperidin-4-yl)amide hydrochloride

https://huagongshe.com/reaction/2227635

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantAmmonium CarbonateHCID 517111—
ReactantHCID 18412364HCID 18412364—
Product1-Methyl-2-[(4-amidinophenyl)oxymethyl]benzimidazol-5-yl-sulfonic acid-n-methyl-n-(1-methylpiperidin-4-yl)amide hydrochlorideHCID 18412592—

Reaction Steps

Prepared analogously to Example 25d from 400 mg of 1-methyl-2-[(4-cyanophenyl)oxymethyl]benzimidazol-5-yl-sulfonic acid-N-methyl-N-(1-methylpiperidin-4-yl)amide with ethanolic hydrochloric acid and ammonium carbonate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06414008B1
Source datasetuspto-grants-2002_07
ORD IDord-13dba9c2568242cfb10d22c420a832ab
Source noteuspto-grants-2002_07