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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2227648Generated: October 27, 2026

Hydrochloric Acid → 1-Methyl-2-[2-(4-amidinophenyl)ethyl]-benzimidazol-5-yl-carboxylic acid-n-phenyl-n-[2-(1h-tetrazol-5-yl)ethyl]-amide-hydrochloride

https://huagongshe.com/reaction/2227648

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantAmmonium CarbonateHCID 517111—
ReactantHCID 178480189HCID 178480189—
SolventEthanolHCID 702—
Product1-Methyl-2-[2-(4-amidinophenyl)ethyl]-benzimidazol-5-yl-carboxylic acid-n-phenyl-n-[2-(1h-tetrazol-5-yl)ethyl]-amide-hydrochlorideHCID 178478915—

Reaction Steps

Prepared analogously to Example 25d from 1-methyl-2-[2-(4-cyanophenyl)ethyl]benzimidazol-5-yl-carboxylic acid-N-phenyl-N-[2-(1H-tetrazol-5-yl)ethyl]amide and ethanolic hydrochloric acid, ethanol, and ammonium carbonate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06414008B1
Source datasetuspto-grants-2002_07
ORD IDord-8a9d97c90bf94db39076da0cf5ccf873
Source noteuspto-grants-2002_07