HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butyl chloroformate → ethyl 3-[[2-[[4-(N-butoxycarbonylcarbamimidoyl)-N-methylanilino]methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butyl chloroformate | HCID 61140 | — |
| Reactant | 1-methyl-2-[N-(4-amidinophenyl)-N-methylaminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide hydrochloride | HCID 18412298 | — |
| Product | ethyl 3-[[2-[[4-(N-butoxycarbonylcarbamimidoyl)-N-methylanilino]methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate | HCID 140409625 | — |
Reaction Steps
Prepared analogously to Example 90 from 1-methyl-2-[N-(4-amidinophenyl)-N-methylaminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide hydrochloride and n-butyl chloroformate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06414008B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-4ac4d5222d684f8c9cbd9c3ea3b1b040 |
| Source note | uspto-grants-2002_07 |