Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2227678Generated: October 31, 2026

Hydrochloric Acid → 1-Methyl-2-[N-(3-amidinopyridin-6-yl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide Hydrochloride

https://huagongshe.com/reaction/2227678

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantAmmonium CarbonateHCID 517111—
ReactantHCID 18412656HCID 18412656—
SolventEthanolHCID 702—
Product1-Methyl-2-[N-(3-amidinopyridin-6-yl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide HydrochlorideHCID 18412653—

Reaction Steps

Prepared analogously to Example 25d from 1-Methyl-2-[N-(3-cyanopyridin-6-yl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide and ethanolic hydrochloric acid, ethanol, and ammonium carbonate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06414008B1
Source datasetuspto-grants-2002_07
ORD IDord-170b37a7cf744840b8d028a267227a9e
Source noteuspto-grants-2002_07