HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-Hydroxyacetophenone → HCID 13376806, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-Hydroxyacetophenone | HCID 7469 | — |
| Reactant | Benzene, 1-fluoro-4-(trifluoromethyl)- | HCID 67873 | — |
| Reactant | 1-[4-(4-fluorophenoxy)phenyl]ethanone | HCID 2759056 | — |
| Product | HCID 13376806 | HCID 13376806 | — |
Reaction Steps
1H NMR (DMSO-d6): δ15.0 (bs, 2H), 9.25 (s, 1H), 8.18 (s, 1H), 7.98 (d, J=8.4 Hz, 2H), 7.77 (d, J=9.0 Hz, 2H), 7.29 (d, J=8.7 Hz, 2H), 7.21 (d, J=8.7 Hz, 2H); mp 230-232° C. The intermediate 1-[4-(4-trifluoromethylphenoxy)phenyl]ethanone was prepared from 4-hydroxyacetophenone and 4-fluorobenzotrifluoride using the method described for the synthesis of 1-[4-(4-fluorophenoxy)phenyl]ethanone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06414011B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-6f1d33eda2544710ad1c88de0fe8cdac |
| Source note | uspto-grants-2002_07 |