Chlorobenzene → 4-(Chloromethyl)phenylacetic acid

HRID 2227897Notes

Reaction equation

HRID 2227897 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([OH:11])=[O:10])=[CH:4][CH:3]=1.[Cl:12]C1C=CC=CC=1>>[Cl:12][CH2:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][C:9]([OH:11])=[O:10])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 7964ChlorobenzeneHCID 248474p-Tolylacetic acid

Product 1

HCID 103134194-(Chloromethyl)phenylacetic acid

Procedure

4-chloromethylphenylacetic acid was prepared in the same manner as in Example 1 except for using 30 g of 4-methyl phenylacetic acid instead of 2-methyl phenylacetic acid and using 90 g of monochlorobenzene.

Sources & evidence

ORD record
ord-92fcf31efd194bacbbbbb7f5c6713744
Source dataset
uspto-grants-2002_07
Patent number
US06414186B1

Reaction notes

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