1,2-Dichloroethane → HCID 59117398, compound

Participants

Reaction Steps

A mixture of product from step D (0.53 g, 1.67 mmol), EDC (0.32 g, 1.67 mmol) and HOBT(0.23 g, 1.67 mmol) was stirred in DMF (30 ml) until solution. This was then treated with L-methionine methyl ester hydrochloride (0.33 g, 1.67 mmol) and N-methylmorpholine (0.37 ml, 3.34 mmol), stirred for 18 hrs at room temperature and then treated with saturated aqueous NaHCO3. The organic phase was evaporated to give the desired starting material (0.15 g, Yield=19.5%).

Provenance & Evidence