反应详情

A solution of methyl 4-methyl-2-trifluoromethylsulfonyloxybenzoate (23.79 g; 7.9 mmol), N-bromosuccinimide (14.19 g; 7.9 mmol), 2,2-azobis (2′-methylproprionitrile) (0.5 g; 3 mmol) and benzoylperoxide (0.5 g; 2 mmol) in tetrachloromethane (250 ml) was heated at reflux for 6 hours. The solid was filtered and the filtrate evaporated to dryness to give methyl 4-bromomethyl-2-trifluoromethylsulfonyloxybenzoate. Yield=55%.

1. temperatureat reflux for 6 hours
2. filtrationThe solid was filtered
3. customthe filtrate evaporated to dryness