Methyl iodide → HCID 18472417, compound

Participants

Reaction Steps

In DMF (10 ml) was dissolved N-[4—(piperidinomethyl)phenyl]-5—(4-methylphenyl)indene-2-carboxamide (400 mg), and to the mixture was added methyl iodide (177 μl). The mixture was stirred at room temperature for 86 hours and concentrated under reduced pressure. The residue was recrystallized from ethyl acetate to give 1-[4-[5—(4-methylphenyl)indene-2-carboxamido]-benzyl]-1-methyl-piperidinium iodide (Compound 61) (516 mg) as pale yellow crystals.

Provenance & Evidence